Old Papers (pre PMC)

M. Huarte, F. Lan, T. Kim, M.W. Vaughn, M. Zaratiegui, R.A. Martienssen, S. Buratowski, and Y. Shi
The fission yeast Jmj2 reverses histone H3 lysine 4 tri-methylation
J Biol Chem. 282:21662-21670 (2007) [Download PDF file]

T. Kim and S. Buratowski
Two Saccharomyces cerevisiae JmjC domain proteins demethylate histone H3 K36 in transcribed regions to promote elongation.
J Biol Chem. 282, 20827-20835 (2007) [Download PDF file]

M.F. Dion, T. Kaplan, M. Kim, S. Buratowski, N. Friedman, O.J. Rando
Dynamics of replication-independent histone turnover in budding yeast.
Science 315, 1405-1408 (2007) [Download PDF file]


M. Kim, L. Vasiljeva, O.J. Rando, A. Zhelkovsky, C. Moore, and S. Buratowski
Distinct pathways for snoRNA and mRNA termination.
Mol. Cell 24, 723-734 (2006) [Download PDF file] [Supplemental Data]

V. Voynov, K. J. Verstrepen, A. Jansen, V. M. Runner, S. Buratowski, and G. R. Fink
Genes with internal repeats require the THO complex for transcription.
Proc. Natl. Acad. Sci. USA 103, 14423-14428 (2006) [Download PDF file]

M.C. Keogh, T.A. Mennella, C. Sawa, S. Berthelet, N.J. Krogan, A. Wolek, V. Podolny, L.R. Carpenter, J.F. Greenblatt, K. Baetz, and S. Buratowski
The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4.
Genes Dev. 2006 Mar 15;20(6):660-5.[Download PDF file] [Supplemental Data]

L Vasiljeva and S. Buratowski
Nrd1 interacts with the nuclear exosome for 3' processing of RNA polymerase II transcripts.
Mol Cell. 2006 Jan 20;21(2):239-48. [Download PDF file] [Supplemental Data] [Nrd1-TAP Mass Spec Data]



D. Chowdhury, M.C. Keogh, H. Ishii, C.L. Peterson, S. Buratowski, and J. Lieberman
gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair.
Mol Cell. 2005 Dec 9;20(5):801-9. Epub 2005 Nov 28.[Download PDF file]

M.C. Keogh, J. A. Kim, M. Downey, J. Fillingham, D. Chowdhury, J.C. Harrison, M. Onishi, N. Datta, S. Galicia, A. Emili, J. Lieberman, X. Shen, S. Buratowski, J.E. Haber, D. Durocher, J.F. Greenblatt, and N.J. Krogan
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery.
Nature. 2006 Jan 26;439(7075):497-501. Epub 2005 Nov 20. [Download PDF file]

M.C. Keogh, S.K. Kurdistani, S.A. Morris, S.H. Ahn, V. Podolny, S.R. Collins, M. Schuldiner, K. Chin, T. Punna, N.J. Thompson, C. Boone, A. Emili, J.S. Weissman, T.R. Hughes, B.D. Strahl, M. Grunstein, J.F. Greenblatt, S. Buratowski, N.J. Krogan
Cotranscriptional Set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex
Cell 123, 593-605 (2005) [Download PDF file]

C.L. Liu, T. Kaplan, M. Kim, S. Buratowski, S.L. Schreiber, N. Friedman, O.J. Rando
Single-nucleosome mapping of histone modifications in S. cerevisiae
PLOS Biology 3, 1753-1769 (2005) [Download PDF file]

S. Buratowski and D. Moazed
Expression and silencing coupled
Nature 435, 1174-1175 (2005) [Download PDF file]

S. Buratowski
Connections between mRNA 3' end processing and transcription termination
Current Opinions in Cell Biology 17, 257-261 (2005) [Download PDF file]

M.E. Bucheli and S. Buratowski
Npl3 is an antagonist of 3' end formation by RNA polymerase II
EMBO Journal 24, 2150-2160 (2005) [Download PDF file] [Download Supplemental Table 1] [Download Supplemental Table 2]



N.J. Krogan, M.H.Y. Lam, J. Fillingham, M.C. Keogh, M. Gebbia, J. Li, N. Datta, G. Cagney, S. Buratowski, A. Emili and J.F. Greenblatt
Proteasome Involvement in the Repair of DNA Double-Strand Breaks
Mol. Cell 16, 1027-1034 (2004) [Download PDF file]

M. Kim, N. J. Krogan, L. Vasiljeva, O.J. Rando, E. Nedea, J. F. Greenblatt, and S. Buratowski
The yeast Rat1 5'-3' exonuclease promotes transcription termination by RNA polymerase II
Nature 432, 517-522 (2004) [Download PDF file] [Supplemental Figures] [Supplemental Table 1]

R. Auty, H. Steen, L.C. Myers, J. Persinger, B. Bartholomew, and S. Buratowski
Purification of active TFIID from Saccharomyces cerevisiae: Extensive promoter contacts and co-activator function
J. Biol. Chem. 279, 49973-49981 (2004) [Download PDF file]

N.J. Krogan, K. Baetz, M.C. Keogh, N. Datta, C. Sawa, T.C.Y. Kwok, N.J. Thompson, M.G. Davey, J. Pootoolal, T.R. Hughes, A. Emili, S. Buratowski, and J. Greenblatt
Regulation of chromosome stability by the histone H2A variant Htz1, the SWR1 chromatin remodeling complex, and the histone acetyltransferase NuA4
Proc. Natl. Acad. Sci. USA 101, 13513-13518 (2004) [Download PDF file]

C. Sawa, E. Nedea, N. Krogan, T. Wada, H. Handa, J. Greenblatt, and S. Buratowski
Bromodomain factor 1 (Bdf1) is phosphorylated by protein kinase CK2
Mol. Cell. Biol. 24, 4374-4742 (2004) [Download PDF file]

O. Matangkasombut, R. Auty, and S. Buratowski
Structure and function of the TFIID complex
Adv. Protein Chem. 67, 67-92 (2004) /sites/buratowski.hms.harvard.edu/files/inline-files/?.pdf

M.C. Keogh and S. Buratowski
Using chromatin immunoprecipitation to map cotranscriptional mRNA processing in Saccharomyces cerevisiae
Methods Mol. Biol. 257, 1-16 (2004) /sites/buratowski.hms.harvard.edu/files/inline-files/?.pdf

S.H. Ahn, M. Kim, and S. Buratowski
Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3' end processing
Mol. Cell 13, 67-76 (2004) [Download PDF file] [Supplemental Information]

M. Kim, S.H. Ahn, N. Krogan, J. Greenblatt, and S. Buratowski
Transitions in RNA polymerase II elongation complexes at the 3' ends of genes
EMBO J. 23, 354-364 (2004) [Download PDF file] [Supplemental Table 1]



N.J. Krogan, M.C. Keogh, N. Datta, C. Sawa, O.W. Ryan, H. Ding, R.A. Haw, J. Pootoolal, A. Tong, V. Canadien, D.P. Richards, X. Wu, A. Emili, T.R. Hughes, S. Buratowski, and J. Greenblatt
A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1
Mol. Cell. 12, 1565-1576 (2003) [Download PDF file] [Supplemental Table 1] [Supplemental Table 2]

S. Buratowski
The CTD code
Nat. Struct. Biol. 10, 679-680 (2003) [Download PDF file]

M.C. Keogh, V. Podolny, and S. Buratowski
Bur1 kinase is required for transcription elongation by RNA polymerase II
Mol. Cell. Biol. 23, 7005-7018 (2003) [Download PDF file]

E. Nedea, X. He, M. Kim, J. Pootoolal, G. Zhong, V. Canadien, T. Hughes, S. Buratowski, C. Moore, and J. Greenblatt
Organization and function of APT, a sub-complex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and snoRNA 3' ends
J. Biol. Chem. 278, 33000-33010 (2003) [Download PDF file]

N.J. Krogan, M. Kim, A. Tong, A. Golshani, G. Cagney, V. Canadien, D. P. Richards, R. K. Beattie, A. Emili, C. Boone, A. Shilatifard, S. Buratowski, and J. Greenblatt
Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II
Mol. Cell. Biol. 23, 4207-4218 (2003) [Download PDF file]

T. Takagi, A. K. Walker, C. Sawa, F. Diehn, Y. Takase, T. K. Blackwell, and S. Buratowski
The Caenorhabditis elegans mRNA 5'-capping enzyme: in vitro and in vivo characterization
J. Biol. Chem. 278, 14174-14184 (2003) [Download PDF file] [Supplementary Tables - oligonucleotides, plasmids, and yeast strains]

O. Matangkasombut and S. Buratowski
Different sensitivities of Bromodomain Factors 1 and 2 to histone H4 acetylation
Mol. Cell 11, 353-363 (2003) [Download PDF file]



R. Buratowski, J. Downs, S. Buratowski
Interdependent interactions between TFIIB, TATA Binding Protein, and DNA
Mol. Cell. Biol. 22, 8735-8743 (2002) [Download PDF file]

N. Krogan, M. Kim, S.H. Ahn, G. Zhong, M.S. Kobor, G. Cagney, A. Emili, A. Shilatifard, S. Buratowski, and J. Greenblatt
RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach
Mol. Cell. Biol. 22, 6979-6992 (2002) [Download PDF file]

T. Takagi, C.J. Cho, R.T.K. Janoo, V. Podolny, Y. Takase, M.C. Keogh, S.A. Woo, L.D. Fresco-Cohen, C.S. Hoffman, and S. Buratowski
Divergent subunit interactions among fungal mRNA 5'-capping machineries
Euk. Cell 1, 448-457 (2002) [Download PDF file]

M.C. Keogh, E. J. Cho, V. Podolny, and S. Buratowski
Kin28 is found within TFIIH and a Kin28-Ccl1-Tfb3 trimer complex with differential sensitivities to T-loop phosphorylation
Mol. Cell. Biol. 22, 1288-1297 (2002) [Download PDF file]



E. J. Cho, M. S. Kobor, M. Kim, J. Greenblatt, and S. Buratowski
Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser2 of the RNA polymerase II C-terminal domain
Genes Dev. 15, 3319-3329 (2001) [Download PDF file]

T. Takagi and S. Buratowski
A Plasmodium falciparum protein related to fungal RNA 5'-triphosphatases
Mol. Biochem. Parasit. 114, 239-244 (2001) [Download PDF file]

W. Selleck, R. Howley, Q. Fang, V. Podolny, M.G. Fried, S. Buratowski, and S. Tan
A histone fold TAF octamer within the yeast TFIID transcriptional coactivator
Nat Struct Biol. 8, 695-700 (2001) [Download PDF file] [Correction to article]



C.R. Rodriguez, E.J. Cho, M.C. Keogh, C.L. Moore, A.L. Greenleaf, and S. Buratowski
Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II
Mol. Cell. Biol. 20, 104-112 (2000) [Download PDF file]

H. Matsuo, T. Moriguchi, T. Takagi, T. Kusakabe, S. Buratowski, M. Sekine, Y. Kyogoku, and G. Wagner
Efficient synthesis of 13C, 15N-labeled RNA containing the cap structure m7GpppA
J. Am. Chem. Soc. 122, 2417-2421 (2000) [Download PDF file]

O. Matangkasombut, R.M. Buratowski, N.W.Swilling, and S. Buratowski
Bromodomain factor 1 corresponds to a missing piece of yeast TFIID
Genes Dev. 14, 951-962 (2000) [Download PDF file]

S. Buratowski
Snapshots of RNA polymerase II transcription initiation
Current Op.Cell Biol. 12, 320-325 (2000) [Download PDF file]

P. Komarnitsky, E.J. Cho, and S. Buratowski
Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription
Genes Dev. 14, 2452-2460 (2000) [Download PDF file]

Y. Takase, T. Takagi, and S. Buratowski
The essential interaction between yeast mRNA capping enzyme subunits is not required for triphosphatase function in vivo
Mol. Cell. Biol. 20, 9307-9316 (2000) [Download PDF file] [Supplemental Information]

C.R. Rodriguez, T. Takagi, E.J. Cho and S. Buratowski
A Saccharomyces cerevisiae RNA 5'-triphosphatase related to mRNA capping enzyme
Nuc. Acids Res. 27, 2181-2188 (1999) [Download PDF file]

T. Deshpande, T. Takagi, L. Hao, S. Buratowski, and H. Charbonneau
Human PIR1 of the Protein-tyrosine Phosphatase Superfamily Has RNA 5'-Triphosphatase and Diphosphatase Activities
J. Biol. Chem. 274, 16590-16594 (1999) [Download PDF file]

E.J. Cho and S. Buratowski
Evidence that Transcription Factor IIB is required for a post-assembly step in transcription initiation
J. Biol. Chem. 274, 25807-25813 (1999) [Download PDF file]

P.B.Komarnitsky, B.Michel, and S. Buratowski
TFIID-specific yeast TAF40 is essential for the majority of RNA polymerase II-mediated transcription in vivo
Genes Dev. 13, 2484-2489 (1999) [Download PDF file]

H. Morehouse, R.M. Buratowski, P.A. Silver, and S. Buratowski
The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein
Proc. Natl. Acad. Sci. USA 96, 12542-12547 (1999) [Download PDF file]

T. Wada, T. Takagi, Y. Yamaguchi, A. Ferdous, T. Imai, S. Hirose, S. Sugimoto, K. Yano, G.A. Hartzog, F. Winston, S. Buratowski, and H. Handa
DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs
Genes & Dev. 12, 343-356 (1998).[Download PDF file]

T. Takagi, G.S. Taylor, T. Kusakabe, H. Charbonneau, and S. Buratowski
A protein tyrosine phosphatase-like protein from baculovirus has RNA 5'-triphosphatase and diphosphatase activities
Proc. Natl. Acad. Sci. USA 95, 9808-9812 (1998). [Download PDF file]

B. Michel, P. Komarnitsky, and S. Buratowski
Histone-like TAFs are essential for transcription in vivo
Mol. Cell 2, 663-673 (1998). [Download PDF file]

E.J. Cho, C.R. Rodriguez, T.Takagi, and S. Buratowski
Allosteric interactions between capping enzyme subunits and the RNA polymerase II C-terminal domain
Genes Dev. 12, 3482-3487 (1998). [Download PDF file]

A. Sachs, and S. Buratowski
Common themes in translational and transcriptional regulation
Trends Biochem. Sci. 22, 189-192 (1997).

T. Takagi, C.R. Moore, F. Diehn, and S. Buratowski
An RNA 5'-triphosphatase related to the protein tyrosine phosphatases
Cell 89, 867-873 (1997).
[Download PDF file]

N. Kuldell, and S. Buratowski
Genetic analysis of the large subunit of yeast transcription factor IIE reveals two regions with distinct functions
Mol. Cell. Biol. 17, 5288-5298 (1997).[Download PDF file]

S. Buratowski
Multiple TATA-binding factors come back into style
Cell 91, 13-15 (1997).[MS Word file] [Download PDF file]

E.J. Cho, T. Takagi, C.R. Moore, and S. Buratowski
mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II C-terminal domain
Genes Dev., 11, 3319-3326. (1997).[Download PDF file]

S. Buratowski and L. Chodosh
Mobility shift DNA-binding assay using gel electrophoresis
in Current Protocols in Molecular Biology (F. Ausubel et al., eds.)
John Wiley & Sons, Inc., New York pp. 12.2.1-12.2.8, 1996

Z. Moqtaderi, J. DePaulo-Yale, K. Struhl, and S. Buratowski
Yeast homologues of higher eukaryotic TFIID subunits
PNAS 93, 14654-14658 (1996).[Download PDF file]

L.D. Fresco and S. Buratowski
Conditional mutants in the yeast mRNA capping enzyme show that the cap enhances, but is not required for, mRNA splicing
RNA 2, 584-596 (1996)

S. Buratowski
Mechanisms of gene activation
Science 270, 1773-1774 (1995)

P. Matsui, J. DePaulo, and S. Buratowski
An interaction between the Tfb1 and Ssl1 subunits of yeast TFIIH is necessary for DNA repair activity
Nuc. Acids Res. 23, 767-772 (1995)

Z. Wang, S. Buratowski, J. Q. Svejstrup, W. J. Feaver, X. Wu, R. D. Kornberg, T. F. Donohue, and E. C. Friedberg
Yeast TFB1 and SSL1 genes encoding subunits of transcription factor IIH (TFIIH) are required for nucleotide excision repair
Mol. Cell. Biol. 15, 2288-2293 (1995) [Download PDF file]

S. Buratowski
RNA polymerase III transcription in the yeast Saccharomyces cerevisiae
Genetic Engineering. (J. Setlow, ed.)
Plenum Press, New York, NY, v. 16, pp. 1-9 (1994)

L.D. Fresco and S. Buratowski
Active site of the mRNA capping enzyme guanylyltransferase from Saccharomyces cerevisiae: Similarity to the nucleotidyl attachment motif of DNA and RNA ligases
Proc. Natl. Acad. Sci. USA 91, 6624-6628 (1994) [Download PDF file]

S. Buratowski
The basics of basal transcription by RNA polymerase II
Cell 77, 1-3 (1994)

S. Buratowski
Yeast Genetics as a Tool for Studying Transcription Initiation
Transcription: Mechanisms and regulation.
Raven Press Series on Molecular and Cellular Biology, vol. 3, (R.C. Conaway and J.W. Conaway, eds.)
Raven Press, New York, NY, pp. 161-170 (1994)

W.J. Feaver, J.Q. Svejstrup, L. Bardwell, A.J. Bardwell, S. Buratowski, K.D. Gulyas, T.F. Donahue, E.C. Friedberg, and R.D. Kornberg
Dual roles of a multiprotein complex from Saccharomyces cerevisiae in transcription and DNA repair
Cell 75, 1379-1387 (1993)

S. Buratowski
Transcription-coupled DNA repair (Response)
Science 262, 439-440 (1993) [Download PDF file]

S. Buratowski and H. Zhou
Functional domains of transcription factor TFIIB
Proc. Natl. Acad. Sci. USA 90, 5633-5637 (1993) [Download PDF file]

S. Buratowski
DNA repair and transcription: The helicase connection
Science 260, 37-38 (1993) [Download PDF file]

S. Buratowski and P.A. Sharp
Initiation of transcription by RNA polymerase II
Transcriptional Regulation. Cold Spring Harbor Monograph Series. (S. McKnight and K, Yamamoto, eds.)
Cold Spring Harbor Press, Cold Spring Harbor, NY, pp.227-246 (1992)

S. Buratowski and H. Zhou
A suppressor of TBP mutations encodes an RNA polymerase III transcription factor homologous to TFIIB
Cell 71, 221-230 (1992) [Download PDF file]

A.J. Koleske, S. Buratowski, M. Nonet, and R.A. Young
A novel transcription factor provides a functional link between RNA polymerase II and TFIID
Cell 69, 883-894 (1992)

S. Buratowski and H. Zhou
TFIID mutants defective for interactions with TFIIA
Science 255, 1130-1132 (1992) [Download PDF file]

P.A. Sharp and S. Buratowski
Regulation of Transcription
Molecular mechanisms and their clinical application in malignancies: Bristol-Myers Squibb Cancer Symposia. v. 12, (D.E. Bergasel and T.W. Mak, eds.),
Academic Press, Inc., Boston, pp. 109-124 (1991)

S. Buratowski, M. Sopta, J. Greenblatt, and P.A. Sharp
RNA polymerase II-associated proteins are required for a DNA conformation change in the transcription initiation complex
Proc. Natl. Acad. Sci. USA 88, 7509-7513 (1991) [Download PDF file]

S. Buratowski and P.A. Sharp
Transcription initiation complexes and upstream activation with RNA polymerase II lacking the largest subunit C-terminal domain
Mol. Cell. Biol. 10, 5562-5564 (1990)

S. Hahn, S. Buratowski, P.A. Sharp, and L. Guarente
Isolation of the gene encoding the yeast TATA-binding protein TFIID: A gene identical to the SPT15 suppressor of TY element insertions
Cell 58, 1173-1181 (1989) [Download PDF file]

S. Hahn, S. Buratowski, P.A. Sharp, and L. Guarente
Identification of a yeast protein homologous in function to the mammalian general transcription factor TFIIA
EMBO J. 8, 3379-3382 (1989)

S. Hahn, S. Buratowski, P.A. Sharp, and L. Guarente
Yeast TATA binding protein TFIID binds to TATA elements with degenerate DNA sequence
Proc. Natl. Acad. Sci. USA 86, 5718-5722 (1989)

L.A. Chodosh, S. Buratowski, and P.A. Sharp
A yeast protein possesses the DNA-binding properties of the adenovirus major late transcription factor
Mol. Cell. Biol. 9, 820-822 (1989)

S. Buratowski, S. Hahn, L. Guarente, and P.A. Sharp
Five intermediate complexes in transcription initiation by RNA polymerase II
Cell 56, 549-561 (1989) [Download PDF file]

S. Buratowski, S. Hahn, P.A. Sharp, and L. Guarente
Function of a yeast TATA element-binding protein in a mammalian transcription system
Nature 334, 37-42 (1988)