News

03/28/2025
msCTD elutions

Working with the Marto Lab, postdocs Deepash Kothiwal and HyunJin Bae produced an improved msCTD system for analyzing phosphorylations on the CTD of RNA pol II subunit Rpb1.  Improved chromatography allows us to separate the different phospho-isoforms for better detection and quantitation. Read about it here in the Journal of Chromatography.

 

03/12/2025

 

Madhura's painting

Congratulations to postdoc Madhura De, whose painting entitled "Stop!" was chosen for the HMS Staff Art Show! You can see it, and lots of other amazing artwork, at Countway Library for the next few months.

01/14/2025

Jongcheol's paper studying activator-SAGA interactions is now out in NSMB!  

Activator-SAGA
10/07/2024

The lab now has two great technicians: Brynn Jacobs is staying for a gap year before heading to medical school, and Mohammed Hijaz just joined us.

10/21/2024

Jongcheol Jeon's paper using single-molecule microscopy (pre-print available on Biorxiv here) to show how transcription activators "recruit" the SAGA histone acetyltransferase complex has been accepted at Nature Structural and Molecular Biology. Congratulations, Jongcheol!

07/01/2024

Madhura De has been awarded a 2024 BCMP Department Postdoctoral Fellowship to support her work imaging interactions between transcription activators and the basal transcription machinery.  Congratulations, Madhura!

09/01/2023

Steve is extraordinarily honored to be named the latest Hamilton Kuhn Professor of Biological Chemistry and Molecular Pharmacology.  This endowed chair was previously held by some giants in biochemistry: Chris Walsh, Gene Kennedy, Albert Baird Hastings, and Otto Folin. Talk about big shoes to fill!

07/10/2023

We're going to miss them a lot, but we're very proud of our two lab techs, Gabby Giordano and Kai Torrens.  Gabby is leaving to start her MD/PhD studies at SUNY Downstate and Kai will be joining the Harvard Physics PhD program.  All the best to both of you!   Stepping into their shoes is Max VanDyck, who just got his undergrad degree in biochemistry from Vassar.  Welcome, Max!